FP7 ERA-NET on Nanosafety
Safe Implementation of Innovative Nanoscience and Nanotechnology


In vitro and in vivo investigations to generate validated toxicity data of graphene nanoplatelets vs a carbon black reference

Project start: 1.6.2015 (tbc)
Duration: 24
Total funding: 356.700 €

Graphene family nanoparticles (GFN) are within the group of carbon-based synthetic nanomaterials (as fullerenes, carbon nanotubes - CNT) and are currently subject of intense efforts to accelerate their toxicological characterization. Certain CNT exhibiting rigidness and a needle-like geometry show accordingly a fibre-specific carcinogenicity. Analogically GFN (i.e. graphene nanoplatelets) seem to have a specific deposition behaviour in the alveolar region due to their nano-thickness and respirability although two dimensions are at microscale. The European Commission is currently driving both innovative material science on GFN as well as the safety testing. Existing toxicity data suggest a lower toxic potential for graphenes as compared to CNT. However, the current database on GFN is scarce. This project will compare commercially available graphenes (i. pure carbon; ii. functionalised with hydroxy or carboxyl groups; iii. graphenes/graphits) using a combined in vitro and in vivo approach.
Otto Creutzenberg

Project coordinator:
Dr. Otto Creutzenberg: otto.creutzenberg@item.fraunhofer.de
Fraunhofer Institute for Toxicology and Experimental Medicine (Fraunhofer ITEM)

Project partners:

1. Fraunhofer Institute for Toxicology and Experimental Medicine (Fraunhofer ITEM),

2. BIOTOX srl,

3. University of Aveiro (UAVR)

The SIINN ERA-NET is funded under the ERA-NET scheme of the Seventh Framework Programme of the European Commission, Research Directorate- General, Grant Agreement No. 265799
© Copyright 2011-2014 Forschungszentrum Jülich GmbH All rights reserved

Cookie policy | Legal Notice

Mail to: ptj-siinn@fz-juelich.de